10 Best Dog Pee Repellent Sprays in 2025 – Reviews & Buyer’s Guide
By Jessica Kim
Updated on
Many dog owners will know from experience that dog urine can be one of the most frustrating and challenging messes to clean up. Along with being stubborn, the odor can cause dogs to continue to pee at the same spots.
One of the best ways to combat repeated urine marking is to use a dog pee-repellent spray. There are many different kinds, so we sorted through the variety and have reviews of some of the best ones that you can find in stores and online. You’ll notice that our list contains many different kinds of sprays that also act as stain removers and deodorizers, which, if you need a repellent, may be welcome additions to your cleaning arsenal as well.
After reading this article, you should be able to have a better grasp of which dog pee repellent spray would work best for you.
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A Quick Comparison of Our Favorites in 2025
Rating | Image | Product | Details | |
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Best Overall |
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Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray |
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Budget Buy |
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Shop Care Super Enzyme Pet Urine & Odor Destroyer |
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Rocco & Roxie Professional Strength Pet Stain & Odor Eliminator |
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Nature’s Miracle Enzymatic Stain Urine Destroyer Foam Aerosol Spray |
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Ion Fusion Severe Pet Urine & Odor Destroyer |
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The 10 Best Dog Pee Repellent Sprays
1. Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray – Best Overall
Cleaner Usage: | Carpets, floors, fabrics, furniture |
Additional Features: | Pet-safe formula, large 32-oz formulation |
The Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray works on multiple surfaces around your home, including hardwood floors. With a bottle size of 32 ounces, you won’t have to worry about replacing this product often. It’s a great option for those who are in the middle of housebreaking puppies or who have elderly dogs and are dealing with frequent accidents around the home.
In addition to urine, this spray tackles vomit, dirt, feces, and unpleasant odors. Instead of using harsh fragrances to cover up smells, the enzymatic formula binds to the stain- and odor-causing bacteria, destroying them for good and leaving behind a neutral scent.
This spray works on fresh or old stains, but if the stains are stubborn, they may require multiple treatments. For surface stains, liberally cover the spot with spray until the entire affected area is covered. Let it sit for 10 minutes, and then blot or wipe it up and let the area air dry. Repeat if necessary.
All in all, we think that the Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray is the best dog pee repellent spray since it effectively lifts odors that draw dogs back to the same spot and prevents repeat marking.
- For use on various surfaces
- Uses enzymes to destroy bacteria and odors
- Combats different stains
- No harsh chemical scent
- Set-in stains and odors may require multiple treatments
2. Shop Care Super Enzyme Pet Urine & Odor Destroyer – Budget Buy
Cleaner Usage: | Hard surfaces, carpet |
Additional Features: | Stain remover, biodegradable, and non-toxic |
Shop Care Super Enzyme Pet Urine & Odor Destroyer is a more affordable option if you’re on a budget. It’s meant for public and commercial use, so it can tackle a wide coverage of space. You can also use it to deodorize garbage bins.
The formula contains enzymes to break down stains and odors. It works on all kinds of surfaces including carpets, bedding, furniture, pavements, walls, and artificial turf. It’s also biodegradable and non-toxic, so it’s safe to use around pets and young children.
It’s recommended to use this product daily to help break down the cycle of urine marking on the same spot. So, it’ll take multiple tries to fully prevent dogs from peeing in unwanted areas. You’ll also have to test for colorfastness because the formula may cause some colors to fade. Therefore, test in a small area before cleaning up a large stain.
- Affordable option
- Versatile uses
- Biodegradable and non-toxic
- May take daily use to prevent dogs from consistent urine marking
3. Rocco & Roxie Supply Co. Professional Strength Pet Stain & Odor Eliminator
Cleaner Usage: | Carpet, kennels, hard surfaces, furniture |
Additional Features: | Stain remover, natural formula |
Rocco & Roxie Supply Co. Professional Strength Pet Stain & Odor Eliminator is another good dog pee repellent spray but is a bit more expensive than the others on our list. It uses natural ingredients and is chemical-free, so you can use it around pets and young children.
The formula contains enzymatic bacteria that activate on contact and feed on ammonia crystals until the stain dissolves. This reaction makes it easier to prevent dogs from peeing in the same spot.
Since the formula doesn’t contain any chlorine or hazardous propellants, it’s less likely to cause the colors of surfaces to fade. This particular cleaner is approved by the Carpet and Rug Institute.
Other than the expensive price, we love this dog pee-repellent spray and believe it’s a great cleaner to have in your supply closet at all times.
- Natural ingredients and chemical-free
- Not known to cause color fading
- Contains natural enzymatic bacteria
- Approved by the Carpet and Rug Institute
- Relatively expensive
4. Nature’s Miracle Dog Enzymatic Stain Urine Destroyer Spray
Cleaner Usage: | Fabric, carpet, hard surfaces, furniture |
Additional Features: | Stain remover, pet-safe formula |
Nature’s Miracle is a reputable brand that consistently produces powerful cleaning formulas that help pet owners keep their homes clean and smelling fresh. The Dog Enzymatic Stain Urine Destroyer Foam is no exception.
This formula comes out as an effective foam that works to penetrate dog urine stains. It contains enzymes that break up and completely eliminate odors so that pets won’t keep urinating in the same spot.
It’s important to be extra cautious when using this product because it can cause colors to fade. It works best on carpets and hard floors and shouldn’t be used on untreated hardwood floors and specialty fabrics, such as silk and wool.
Overall, Nature’s Miracle Dog Enzymatic Stain Urine Destroyer Foam is a great dog pee repellent spray because it’s specifically designed to lift and remove urine stains and deodorize and break down odors for good.
- Enzymes break down urine
- Prevents urinating in the same area
- Works on most types of flooring
- Can cause colors to fade on some surfaces
5. Ion Fusion Severe Pet Urine & Odor Destroyer
Cleaner Usage: | Carpets, furniture, hard surfaces |
Additional Features: | Stain remover, bio-degradable and non-toxic |
The Ion Fusion Severe Pet Urine & Odor Destroyer uses an ion formula to tackle urine stains and remove odors. This non-toxic formula works on contact and removes stains while being gentle on surfaces. It’s biodegradable and completely safe to use around animals.
The bottle is also one of the most ergonomic options you can find. It has a comfortable grip so that your hand doesn’t feel strained while you apply the formula to the stain.
The formula has a mixed berry scent which is pleasant for some. However, individuals with scent sensitivities may not enjoy the smell and feel that it’s too strong.
- Non-toxic and biodegradable
- Works on contact
- Gentle on surfaces
- Ergonomic bottle design
- Has a strong berry scent
6. Tough Stuff Urine Odor & Stain Eliminator
Cleaner Usage: | Carpet, bedding, furniture |
Additional Features: | Stain remover |
Tough Stuff Urine Odor & Stain Eliminator is a spray that’s specifically used for carpets and upholsteries. So, it’s not as effective with reducing and eliminating stains and odors on hard surfaces. However, it does a great job of working to fight stubborn stains.
This formula contains enzymes and also has the Carpet and Rug Institute Seal of Approval. Once you spray it, it works to change the chemical composition of urine stains so that they’re easier to remove. It completely deodorizes and breaks down odors, so you don’t have to worry that it’s just masking smells.
- Has Carpet and Rug Institute Seal of Approval
- Completely breaks down odors
- Works great with carpet and upholstery
- Not for hard surfaces
7. Simple Solution Pet Urine Destroyer
Cleaner Usage: | Carpets, upholstery, hard surfaces |
Additional Features: | Stain remover, laundry prewash, carpet cleaner solution |
Simple Solution Pet Urine Destroyer is another product that has received the Carpet and Rug Institute’s Seal of Approval. So, you can purchase it knowing that it has a powerful formula that can clean up stains and odors and prevent dogs from urinating in the same spot.
This spray is another enzyme cleaner that works hard on stains and can work on all kinds of surfaces. It shouldn’t damage colorfast carpets, but it doesn’t hurt to be safe and test it out on a small area first. It can also be used as a laundry pre-wash or with carpet cleaner machines.
The whole process of using this cleaner can take up to 48 hours. Once you spray it, you have to wait about 10 minutes for the spray to activate and break down the stain. Then, after you blot it out, it can take up to 48 hours to dry. It’s important to keep pets and children away from treated areas during this time because it’s not safe.
- Has Carpet and Rug Institute Seal of Approval
- Works on all kinds of surfaces
- Can be used as laundry pre-wash
- Takes a long time to dry
- Not safe around children and pets
8. Urine Gone Pet Stain & Odor Eliminator
Cleaner Usage: | Carpet, wood, tile, bathrooms, sofas, bedding, litter boxes |
Additional Features: | Stain remover, non-toxic |
Urine Gone Pet Stain & Odor Eliminator tends to be a relatively affordable enzyme spray. It does a great job of getting into carpet fibers to lift stains and the odors associated with them. This spray also works on all kinds of surfaces, including carpets, wood, tile, porcelain, and upholstery.
Another feature to note is that this formula works effectively against accidents created by pets and people. So, it’s great to have around the house if you have very young children. It doesn’t seem to have any added fragrances, but it also doesn’t have a very pleasant smell. With that being said, a room may not smell very good while you’re in the process of using this spray to clean up stains.
- Relatively affordable
- Works on multiple surfaces
- Works on pet and people accidents
- Some users say it has an unpleasant smell
9. Shout Pets Oxy Urine Destroyer for Carpeting & Upholstery
Cleaner Usage: | Carpet and upholstery |
Additional Features: | Stain remover |
Shout Pets Oxy Urine Destroyer for Carpeting & Upholstery is another relatively affordable dog pee repellent spray. It’s oxygen-powered and starts breaking down stains immediately on contact.
Since it completely removes stains and odors, it’s great at preventing dogs from soiling in the same spots. Just make sure to use this spray on a small area first because it can end up damaging or discoloring fabrics.
This formula also only works on carpets and upholstery. So, it can be a money-saving option if you’re having more issues with carpets. However, if you have mostly hardwood floors, it’s best to move on to a different product.
- Relatively affordable
- Starts working on contact
- Can completely remove stains and odors
- Only works on carpets and upholstery
- May discolor some surfaces
10. Nature’s Miracle No More Marking Pet Stain & Odor Remover
Cleaner Usage: | Any surface |
Additional Features: | Stain remover, laundry pre-wash |
Nature’s Miracle No More Marking Pet Stain & Odor Remover does a great job of removing most pet stains, but it does require some extra work to get rid of old and stubborn stains. It can take about 2 weeks for the treatment to dry, and the formula isn’t safe around pets and children, so the entire process can end up being quite inconvenient.
However, we did notice that this spray is very intentional about not having pets revisit the same spots. It includes scents that are pleasant to people, such as citrus and cinnamon, but dogs don’t typically like these smells. So, they’re more likely to avoid treated areas.
- Works on multiple surfaces
- Uses scents to deter dogs
- Not as effective on old stains
- Takes a long time to dry
Buyer’s Guide: Choosing the Right Dog Repellent Spray
Now that you know what options are available, here are some key things to look for when shopping for a good dog pee-repellent spray.
Enzymatic Formula
Some of the most effective dog pee repellent sprays will contain enzymes in them. These enzymes help break down the protein and composition of urine stains so that they both lift the color of the stain as well as the odor.
So, you’ll probably have a better experience using enzymatic formulas because they’re often specifically made to clean up urine. This almost means that they’ll destroy odors, rather than mask them, which helps to prevent dogs from urinating on the same spots.
Ergonomic Design
There’s a good chance that you’ll have to use your spray repeatedly, especially when you’re first cleaning up after your dog. So, make the process as comfortable as possible by finding a bottle that also has an ergonomic design. Look for spray nozzles that don’t require too much force to spray the formula.
Also, make sure that the bottle is lightweight. Since it’s carrying a lot of liquid, you want it to be as light as possible.
Color-safe Products
A lot of powerful formulas may be able to remove stains, but they can also damage surfaces during the process. When shopping for a new dog pee repellent spray, pay special attention to if it only works on specific types of surfaces.
Make sure to read the label to see if it recommends testing out small areas first and if it can’t be used on more delicate materials, such as leather, silk, and wool.
Our Dog Pee Repellent Sprays Selection Process
When it comes to selecting products, Hepper has a committed team of writers and editors who work closely with licensed veterinarians to find the very best in today’s market. Together, they consider customer feedback, brand reputation, veterinary expertise, and whenever possible, hands-on testing. We aim to select and review the highest-quality products to help you make informed choices that meet both your and your pet’s needs.
Why Trust Hepper?
Since 2007, Hepper has been a trusted and growing online brand and resource with the edge of creating and retailing our own line of cat furniture, toys, and gear, and pet consumables, giving us valuable insights into how to choose dog pee repellent sprays. Our driven team of pet-loving writers, editors, and veterinarians is dedicated to empowering our readers to make the best decisions for their animal companions. Our priority lies in providing top-notch information and recommendations. Our team is genuinely invested in the health and well-being of all pets worldwide, believing that expert knowledge is crucial for achieving this goal.
Conclusion
Our reviews reveal that the Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray is the best dog pee repellent spray because it works on multiple surfaces around your home, including hardwood floors. Our runner-up is Shop Care Super Enzyme Pet Urine & Odor Destroyer. It’s versatile and offers a lot of coverage while being budget-friendly.
Potty training dogs can be a challenging process that can require different techniques and tools. Sprays can be extremely effective tools that help you keep your house clean while preventing dogs from urinating in the same spaces.
Featured Image Credit: New Africa, Shutterstock