Hepper is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

10 Best Flea Drops for Cats – 2022 Reviews & Top Picks

Nicole Cosgrove Profile Picture

By Nicole Cosgrove

cat flea treatment

Cats, whether they love to stay indoors or outdoors, are prone to catching fleas. When this happens, your pet is likely to itch, scratch, develop rashes, and experience significant discomfort. As a pet owner, you have to find the best flea treatment.

There are different flea treatment options, including flea collars, oral tablets, shampoos, and drops. We recommend flea drops as it is an effective flea control option. Usually, you apply the spot-on between your cat’s shoulder blades, which is a relatively easy task.

However, if you have started researching on best flea drops for cats, you must have observed that there are dozens of products in the market. This is why we have rounded up the ten best flea drops for cats to help you decide what product is suitable for your furry pet. These flea drops work effectively at killing flea life cycles and preventing re-infestations.

A Quick Comparison of Our Favorites in 2022

Rating Image Product Details
Best Overall
Winner
Bayer Advantage Cat Flea Treatment Bayer Advantage Cat Flea Treatment
  • Veterinarian recommended
  • Waterproof formula
  • Breaks flea life cycle
  • Best Value
    Second place
    Advecta Plus Cat Flea Squeeze-On Advecta Plus Cat Flea Squeeze-On
  • It kills all life stages of fleas
  • Waterproof
  • Fragrance-free
  • Premium Choice
    Third place
    Revolution Topical Solution for Cats Revolution Topical Solution for Cats
  • Prevents and controls flea infestations
  • Controls ear mite infestations
  • Protects against roundworms, hookworms, and heartworm disease
  • Best for Kittens
    Virbac Effipro Cat Topical Solution Virbac Effipro Cat Topical Solution
  • Effective for three months
  • Kills fleas upon contact
  • Suitable for kittens above eight weeks
  • Advantage Flea Treatment for Small Cats Advantage Flea Treatment for Small Cats
  • Vet recommended
  • Waterproof formula
  • Effective for a month
  • The 10 Best Flea Drops for Cats

    1. Bayer Advantage II Large Cat Flea Treatment – Best Overall

    Advantage II Flea Spot Treatment for Cats

    Check Price on Chewy
    Lifestage Adult
    Health Condition Fleas
    Duration 1 Month

    The Bayer Advantage II Flea Treatment kills fleas upon contact, a reason we recommend it as the best overall flea drops for cats. Additionally, the treatment destroys flea eggs and larvae to break the flea life cycle.

    Not only is the Bayer Advantage II effective, but it is also veterinarian recommended. You can use it on kittens and cats at eight weeks or older. It starts working within 12 hours after application.

    Its active ingredients, imidacloprid, and pyriproxyfen do not cause fleas to bite your cat. This means that your cat will experience minor irritation after using this treatment.

    The formula works for four weeks. Since it is waterproof, you can bathe your pet without worry. This topical application is available in 2-, 4-, and 6-treatment packs.

    Pros
    • Veterinarian recommended
    • Waterproof formula
    • Breaks flea life cycle
    • Less irritation
    Cons
    • Not for kittens under eight weeks
    • Pricey
    • Suitable for cats over 9 lbs.

    2. Advecta Plus Flea Squeeze-On for Cats – Best Value

    Advecta Plus Flea Squeeze-On, Flea Prevention for Cats

    Lifestage Adult, Senior
    Health Condition Fleas
    Duration 4 Months

    Advecta Plus uses the same active ingredients as Advantage II, imidacloprid and pyriproxyfen, to break the flea life cycle and prevent re-infestation. This squeeze-on is practical and offers you value for your money.

    In just 12 hours of application, this flea treatment kills adult fleas. Besides, it is effective for up to 4 months. The waterproof formula remains active and provides protection should your pet get wet.

    The squeeze-on is convenient and easy to apply. For this, we recommend the Advecta Plus Squeeze-On as the best flea drops for cats for the money.

    Pros
    • It kills all life stages of fleas
    • Waterproof
    • Fragrance-free
    • Easy to use
    • Protects for up to 4 months
    Cons
    • Some cats experience severe side effects

    3. Revolution Topical Solution for Cats – Premium Choice

    Revolution Topical Solution for Cats

    Lifestage Kittens, Adults, Pregnant and Lactating Cats
    Health Condition Fleas, Ear mites, Heartworms, Roundworms, Hookworms
    Duration 1 Month

    Revolution Topical Solution controls flea infestation and kills adult fleas. When applied, this topical solution works effectively for 30 days. Like regular flea drops, use this medication on your kitty’s skin to stop flea eggs from hatching and kill the existing ones.

    Apart from flea prevention, Revolution Topical Solution also prevents and treats ear mites, hookworms, roundworms, and heartworm disease. It includes active ingredients such as selamectin, sarolaner, isopropyl alcohol, and butylated hydroxytoluene, which is why you may need a vet’s prescription before administering.

    As great as this solution is, it may have possible side effects on your cat. These include hair loss at the application site with or without inflammation, vomiting, diarrhea, anorexia, lethargy, rapid breathing, hives, and fever. It is best to consult your vet before administering this solution.

    Pros
    • Prevents and controls flea infestations
    • Controls ear mite infestations
    • Protects against roundworms, hookworms, and heartworm disease
    • Suitable for kittens up to 8 weeks old, pregnant and lactating cats
    Cons
    • Adverse side effects
    • Expensive
    • Prescription needed

    4. Virbac Effipro Plus Cat Topical Solution – Best for Kittens

    Virbac Effipro PLUS Topical Solution For Cats

    Lifestage Kittens, Adults, Seniors
    Health Condition Flea, Ticks
    Duration 3 Months

    The Vibrac Effipro Plus Topical Solution is the best flea drop for kittens above eight weeks. It is convenient, effective, fast-acting, and long-lasting. The two main active ingredients are Fipronil and pyriproxyfen.

    The solution starts working upon contact to control chewing lice, mosquitoes, ticks, and fleas. It destroys flea eggs, larvae, and pupae to prevent re-infestation for up to 3 months. This topical solution is easy to apply and waterproof.

    Pros
    • Effective for three months
    • Kills fleas upon contact
    • Suitable for kittens above eight weeks
    • Waterproof
    Cons
    • Not fragrance-free
    • Not for pregnant or lactating cats

    5. Advantage II Flea Spot Treatment for Small Cats

    Advantage II Flea Spot Treatment for Cats

    Lifestage Adult
    Health Condition Fleas
    Duration 1 Month

    If your flea-infested cat weighs 5 to 9 lbs., use Advantage II Flea Spot Treatment. It combines two active ingredients, Imidacloprid and Pyriproxyfen. Imidacloprid paralyzes and kills adult fleas, while pyriproxyfen kills flea eggs and larvae.

    The formula kills fleas upon contact, and they do not bite your cat to die. A single dose of this treatment lasts for a month. However, if your pet has a severe infestation, it would be best to reapply the treatment within the month.

    This topical solution is waterproof, so it is okay to bathe your cat 24 hours after application.

    Pros
    • It kills flea eggs, larvae, and adults
    • Vet recommended
    • Waterproof formula
    • Effective for a month
    Cons
    • Not suitable for large cats

    6. Vectra Green Flea Control for Cats

    Vectra Green For Large Cats

    Lifestage Adult
    Health Condition Fleas
    Duration 1 Month

    Fleas transmit diseases like tularemia, bartonellosis, rickettsiosis, and flea allergy dermatitis, which often result in pain and discomfort for your cat. It is a relief that Vectra Green for Cats solution controls fleas from all life stages, including kittens, over eight weeks. It prevents re-infestation and transmission of diseases.

    This flea drop is effective and long-lasting. It kills fleas upon contact and within 6 hours after use. This means your cat will not experience irritation and discomfort since fleas do not need to bite to die.

    One application protects for 30 days. Vectra Green’s active ingredients include dinotefuran and pyriproxyfen.

    Pros
    • It kills fleas on contact
    • Effective and long-lasting
    • Protects cats against diseases
    • No irritation
    Cons
    • Available from licensed veterinarians

    7. Cheristin Flea Spot Treatment

    Cheristin Flea Spot Treatment for Cats

    Lifestage Adult
    Health Condition Fleas
    Duration up to 6 Weeks

    The Cheristin Flea Spot Treatment is a safe and effective formula. It kills and prevents fleas minutes after application. For this, expect your kitty to stop meowing and scratching within 12 hours of application since this formula kills more than 98% of fleas.

    Cheristin Flea treatment is easy to apply. It comes in a non-greasy applicator that gets into the skin. One dose remains effective for 4 to 6 weeks.

    The included active ingredient is Spinetoram. It effectively kills adult fleas but is not as effective on flea eggs, pupae, and larvae. You may have to reapply the solution once these eggs develop or use other flea treatment solutions like oral tablets.

    Pros
    • Non-greasy
    • Quick drying
    • It kills more than 98% of fleas
    • Effective for four plus weeks
    Cons
    • Not effective on flea eggs, larvae, and pupae

    8. Catego Flea & Tick Spot Treatment

    Catego Flea & Tick Spot Treatment for Cats

    Lifestage Adult, Kitten, Senior
    Health Condition Fleas, Ticks
    Duration 1 Month

    If you are looking for a fast relief flea drop, consider Catego Flea & Tick Spot Treatment. It kills fleas within 6 hours of application. It also destroys flea eggs, flea larvae, chewing lice, and ticks.

    The treatment includes a dropper with a patented applicator tip, which makes the application effortless. The solution is non-greasy and quick-drying to reduce messes.

    You can use this spot treatment on cats over eight weeks and weighing 1.5 pounds and above.

    Pros
    • Effective for a month
    • Quick-drying
    • Easy administration
    • Offers fast relief
    Cons
    • Not effective for all cats

    9. Frontline Plus for Cats

    Frontline Plus Flea & Tick Spot Treatment for Cats

    Lifestage Kitten, Adult, Senior
    Health Condition Fleas, Ticks
    Duration 1 Month

    Protect your cat from fleas and ticks with the Frontline Plus for Cats. It breaks the flea life cycle by preventing flea eggs from hatching, destroying flea larvae, flea pupae, and adult fleas. The treatment also kills chewing lice and ticks.

    Frontline Plus contains Fipronil and (S)-methoprene as its two main ingredients. They are effective in controlling flea infestations. The solution is waterproof, fast-acting, and works for 30 days.

    It is suitable for cats over 1.5 lbs. The chances are that your kitty may experience irritation at the application site, but it should ease with time. However, consult your vet if the irritation lasts for days and becomes severe.

    Pros
    • Waterproof protection
    • Disrupts flea life cycle
    • Works for 30 days
    • Offers fast-acting and long-lasting protection
    Cons
    • Not ideal for cats under 1.5 lbs.

    10. TevraPet FirstAct Plus Flea & Tick Spot Treatment

    TevraPet FirstAct Plus Flea & Tick Spot Treatment for Cats

    Lifestage Adult
    Health Condition Fleas
    Duration 1 Month

    TevraPet FirstAct Plus is vet-formulated to kill flea eggs and larvae, chewing lice, ticks, and adult fleas. The topical liquid treatment combines Fipronil and (S)-methoprene to kill emerging and existing fleas.

    The formula is fast-acting and offers relief within 12 hours of application. It is waterproof too and effective for a month. This treatment is suitable for cats weighing more than 1.5 pounds.

    Pros
    • It kills fleas, ticks, and chewing lice
    • Consists three treatments
    • It prevents the development of flea eggs and larvae
    • Waterproof
    Cons
    • Not for cats under 1.5 pounds

    Buyer’s Guide: Choosing the Best Flea Drops for Cats

    Before you pick the first flea drop you find, here are three factors to keep in mind.

    Usage

    Flea drops come in various forms. Some are intended to kill adult fleas, while others destroy flea eggs, larvae, and pupae, thus breaking the pest’s life cycle. So, when choosing a flea drop, read the label carefully to go for one that kills the four life stages of a flea. This will save you money and ease your pet’s discomfort.

    Multi-Purpose Products

    Some flea drops are designed to kill adult fleas but not flea eggs effectively. On the other hand, some are labeled broad-spectrum, and they kill the life cycle of fleas, plus as ticks and other pets.

    Therefore, take time to confirm with your vet whether the flea drop medication you are considering is effective against the type of fleas found in your area. It wouldn’t hurt if you chose a broad-spectrum flea drop that kills ticks, roundworms, or hookworms too.

    Dogs Vs. Cat’s Flea Drops

    You may have had incidences where your vet recommended the same medication for your cat and dog. However, that principle does not apply to flea drops. Do not choose a flea intended for dogs as it may contain certain harmful, even deadly ingredients on your cat. Stick to flea drops specifically made for cats.

    cat being treated from ticks and fleas

    Other Types of Flea Control Treatments

    Flea drops are effective flea control treatments since they are absorbed in your cat’s system and transported more thoroughly throughout the body. But there are other flea control treatments out there. Here are other options to consider.

    Flea Collars

    Flea collars are effective in flea control and come in two designs; solid and liquid insecticides. Collars with solid insecticide and resin wear away over time as the insecticide is released over time.

    It may be absorbed into the top layers of the cat’s skin or dispersed.  On the other hand, collars with liquid insecticide release gas to repel fleas, not kill them.

    Flea collars begin to work within 24 hours, and some can last for up to 8 months. They contain active ingredients such as pyrethroids, organophosphates, permethrin, and methoprene.

    Oral Medication

    These flea control products are pills administered by mouth. These pills are the safest option for pet owners worried about exposing flea medication to other pets and children. Some oral tablets work for a month, while some need frequent administering.

    Flea Shampoos

    Flea shampoos are effective at killing adult fleas when you use them for bathing your cat. The best shampoos are non-toxic and mild.

    They act as a base for flea prevention without harming your cat. In addition, your furry friend benefits from having clean and healthy fur.

    However, flea shampoos are the least effective flea control treatments compared to flea drops, collars, and oral tablets.

    cat bath
    Image Credit: Irina Kozorog, Shutterstock

    Flea Sprays

    Flea sprays come in handy when you use them alongside other flea control treatments like shampoos. However, ensure that the spray is non-toxic and safe for your kitty and family.

    You can spray some on your pet’s bedding or all over your cat’s body. Massage it into the skin without touching the cat’s eyes, nose, and mouth.

    Why You Should Get Rid of Fleas

    Flea bites are cause irritation, discomfort, and stress for your kitty. Some cats are allergic to proteins found in flea saliva and may itch and scratch once a flea bites them.

    Flea bites can lead to lesions and infections when left untreated, making your pet’s life miserable. It not only kills

    Additionally, adult fleas can cause weakness, anemia, and death in young kittens as they mainly feed on blood. The fleas can also transmit ‘cat scratch disease (CSD) between you and your cat. CSD is a bacterial infection that leads to the swelling of lymph nodes.

    Related: What Happens If a Cat Licks Flea Medicine? (Vet Answer)

    Conclusion

    Only the best flea drops work effectively to kill the four life stages of fleas; eggs, larvae, pupae, and adults. This is why we recommend the Bayer Advantage II Flea Treatment. This vet-recommended treatment is engineered to protect your cat from flea eggs, flea larvae, pupae, and adults.

    If you are looking for the best value flea drop, try the Advecta Plus Squeeze-On. Its active ingredients effectively kill all life stages of fleas and works within 12 hours of application.

    Vibrac Effipro Plus Topical Solution is your best bet if your kitten has fleas. It is convenient, long-lasting, quick-acting, and effective at killing fleas, ticks, chewing lice, and mosquitoes.

    Now you have the ten best flea drops for cats. We hope that this review helps you find the best solution for your flea-infested pet.


    Featured Image Credit: Okssi, Shutterstock

    Related Articles

    Further Reading

    Vet Articles

    Latest Vet Answers

    The latest veterinarians' answers to questions from our database

    hepperorangebluebadgebuttonfeb