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Gabapentin for Cats (Vet Answer): FAQs, Uses, Dosage & Side Effects

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By Dr. Chantal Villeneuve

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Written by

Dr. Chantal Villeneuve

MS BVetMed (Veterinarian)

The information is current and up-to-date in accordance with the latest veterinarian research.

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Gabapentin is a central nervous system medication used to manage pain, anxiety, or seizures. It was originally formulated as a treatment for seizures in humans, but it is very effective for pain relief and anxiety in animals. It can make cats slightly drowsy and uncoordinated but has few side effects, especially compared to other pain-relief medications.

What Is Gabapentin?

Gabapentin is an off-label drug. While it was made for humans, many veterinarians will prescribe human tablets or capsules for cats, and it is considered a safe medication for them.

The most common brand name is Neurontin, others include:

  • Progresse
  • Equipax
  • Gaborone
  • Aclonium
  • Gralise
  • Gantin
  • Neurostil

Because it is given off-label, it is extra important to follow your veterinarian’s prescription and not the label on the box. And do not give gabapentin to your cat without a prescription—some forms of human gabapentin contain xylitol which is toxic to cats.

Gabapentin has three primary uses: pain relief, anxiety, or seizures.

  • Pain relief: Gabapentin is used as long-term pain relief for chronic conditions such as arthritis. It is also used with other medications to manage pain after surgery or an injury.
  • Anxiety treatment: Gabapentin is used for stressful events. For example, if given 2–3 hours before a vet visit, gabapentin can help keep a cat calm during the visit, and its effects quickly fall off after 8-12 hours, so they are quickly back to normal.
  • Seizure control: Gabapentin is used long-term to manage recurring seizures. Other medications are used to stop active seizures, but gabapentin is used to help prevent seizures from happening in the first place. It is used in conjunction with other anti-seizure medications as part of a daily long-term treatment plan.

person petting a sick cat
Image Credit: Alexander Andrews, Unsplash

How Is Gabapentin Given?

Gabapentin is usually given every 8–12 hours, depending on the condition being treated.

The amount given will vary depending on three important things:
  1. The size of your cat: Your vet will calculate the dose according to your cat’s weight.
  2. The condition being treated: Pain, seizures, and anxiety all need different levels of medication to be effective.
  3. How your cat responds: Especially when treating seizures or anxiety, instead of starting at the highest dose and hoping for the best, many vets will start with a low dose and slowly, incrementally, increase the dosage depending on how your cat responds.

What Happens if You Miss a Dose?

This depends on why your cat was given gabapentin in the first place. If you miss a dose, consult with your vet, they will most likely say to give the next dose as normal. Do not give more next time.

  • If the gabapentin is treating chronic pain—arthritis, for example—a cat will probably just be a little stiffer until their next dose. But if it is after surgery, the consequences of that pain can be significant. A cat that misses a dose of pain relief is more likely to chew, scratch, or cause injury to its surgical site. They are also more likely to become severely stressed, to not eat or drink, or to injure themselves in some other way. Either way, a cat in pain will take longer to heal after surgery or injury.
  • For anxiety, if gabapentin is not given before a vet visit, or as more often happens, it’s given fifteen minutes before the appointment instead of two hours beforehand, then you’re probably going to have to reschedule your visit because the medication has not had enough time to take effect.
  • If you miss a dose, your cat is more likely to have a seizure. Seizure treatment tries to maintain a steady state of medication in the body because ups and downs of medication concentration in the body can trigger seizures.

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Image Credit: Alice Rodnova, Shutterstock

Potential Side Effects of Gabapentin

The beauty of gabapentin is that it has very few side effects. The only real side effect is some level of sedation, which can vary from drowsiness to being unsteady on their feet to just taking a few extra naps.

Frequently Asked Questions (FAQs)

Can I give gabapentin with food?

Technically, it can be given with or without food; the medication is not affected either way.

But it does not taste very good, so it often must be hidden in treats or coaxed down.

It is tempting to hide the pills in a bowl of food, but cats are sneaky and are very good at hiding the fact that they did not eat their medication. So, usually, giving it in their absolute favorite treat right before a meal—when they are hungriest—works best. That way you can watch them swallow the whole thing.

Getting your cat to swallow the medication is probably the worst thing about gabapentin.

maine coon cat eating
Image Credit: Lita Keire, Shutterstock

Why am I giving my cat so many pills for pain?

Gabapentin is used to relieve pain because it does not have many side effects, but it is probably not enough to manage severe pain alone. Opioids, for example, are the best at relieving pain, and NSAIDs are great for reducing inflammation, but both can have some negative side effects.

Gabapentin does not have these side effects, but it does not block pain as effectively as most opioids and does not reduce inflammation like NSAIDs. So, in cases of severe pain, gabapentin is often used in combination with other pain meds so that a smaller dose of opioids and NSAIDs can be used, but more pain relief is achieved.

In fact, using more than one type of pain relief is considered safer and more effective than relying on just one type. This type of medication is called multimodal analgesia (pain relief). It uses more than one medication so that multiple points along the pain pathway are blocked, so pain relief is increased while the amount and side effects of individual medications are reduced.

Why am I giving my cat so many pills for seizures?

There are numerous medications used for controlling seizures, and while gabapentin can be helpful, it is probably not the most effective, especially if it is used alone. In other words, other drugs are more effective at treating seizures, but when gabapentin is added on top of these together, they can become even more effective than when used alone.

Long-term seizure control includes daily medicating and carefully titrating medications for each individual. Slowly increase the doses of each drug until the best control is reached while keeping the side effects of the medications used to a minimum.

giving cat a pill
Image Credit: Dora Zett, Shutterstock


Not much is more complicated than treating problems in the nervous system, such as pain, seizures, and anxiety. Gabapentin is one of the many medications veterinarians use, often in combination with other medications, to manage these complex conditions. Communicating with your vet and carefully watching your cat’s response to medication will help everyone find the dose that works best for your cat. Do not stop giving gabapentin without discussing it with your vet.

Just like any medication, gabapentin can have side effects, particularly at high doses as it can cause drowsiness and incoordination. The dose prescribed will depend on your cat’s medical condition, body condition, how they respond to the medication, and other medications used at the same time.

See Also: 

  • Ramsey, I. (2008). BSAVA small animal formulary (No. Ed. 6). British Small Animal Veterinary Association.
  • The Merck Veterinary Manual. Whitehouse Station, NJ: Merck & Co., Inc. 2023

Featured Image Credit: Piskova Photo, Shutterstock

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