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Iris Melanosis in Cats: Signs, Causes & Treatment (Vet Answer)

Dr. Marta Vidal-Abarca

By Dr. Marta Vidal-Abarca

russian blue cat with iris melanosis

Vet approved

Dr. Marta Vidal-Abarca Photo

Written by

Dr. Marta Vidal-Abarca

BVSc GPCert (Ophthal) MRCVS (Veterinarian)

The information is current and up-to-date in accordance with the latest veterinarian research.

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Cats are fascinating creatures that make great pets. They have unique physical traits that make them stand out from other animals. One such feature is their eye color, which can vary from bright blue to stunning green or amber. However, some cats develop a benign condition called iris melanosis, which can cause their eyes to change color and develop dark spots. On other occasions, some cats develop a type of malignant tumor called feline diffuse iris melanoma which can be impossible to differentiate from iris melanosis without a biopsy.

If you’re a cat owner, it’s crucial to understand the differences between these two conditions and identify them early on to prevent any significant damage.

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What Exactly Is Iris Melanosis?

Iris melanosis in cats is a condition where the iris, which is the colored part of the eye, develops dark spots. The spots may be small or large and can be black or brown in color. The condition is caused by the overproduction of melanin, which is the pigment that gives color to the skin, hair, and eyes. Iris melanosis is a benign condition, which means that it’s not cancerous, but it must be watched carefully since, in some cases, can lead to a worrying scenario.

The spots caused by iris melanosis can be mistaken for a more serious condition called iris melanoma, which is a type of cancer that affects the iris. However, unlike iris melanoma, iris melanosis doesn’t spread to other parts of the body and doesn’t cause any significant harm to the cat’s health. Nevertheless, it’s still essential to identify the change in your cat’s iris and seek advice to understand what is happening in your cat’s eyes.

Iris melanosis can affect cats of all ages and breeds.

an orange tabby domestic shorthair cat with iris melanosis in its eyes
Image By: Mary Swift, Shutterstock

Where Are the Signs of Iris Melanosis in Cats?

The signs of iris melanosis in cats can vary from subtle to more obvious, depending on the extent of the color change. Cats with iris melanosis will develop flat dark spots in the iris that look like freckles. The spots can be black or brown in color and may be tiny or large. The spots may also be unevenly distributed on the iris, giving it a mottled appearance. The changes can occur in one or both eyes.

iris melanosis in adult cat
Image By: Todorean-Gabriel, Shutterstock

What Causes Iris Melanosis in Cats?

The exact cause of iris melanosis in cats is unknown. While this change in pigmentation can remain benign throughout a cat’s life, it can, at any point, turn into iris melanoma with no way of predicting it. The reason why melanocytes start becoming malignant and infiltrate the deeper layer of the iris remains unknown.

How Do Vets Diagnose Cats With Iris Melanosis?

Any cat that suffers from a change, even the subtlest, in the color of the iris should get a comprehensive eye exam by a veterinarian or veterinary ophthalmologist. The vet will examine the cat’s eyes using different non-invasive methods such as an ophthalmoscope, a slit lamp, intraocular measurement, and gonioscopy. They may also perform other tests, such as an ultrasound, and a biopsy might be recommended depending on findings.

If the vet suspects that the cat has iris melanosis, they may recommend monitoring the condition very closely to detect early if it progresses to iris melanoma. Nowadays, there is no way to predict how the melanocytes will behave and if they will become malignant at any point. If your vet suspects that your cat is suffering from an iris melanoma, they may recommend having the eye removed (enucleation) to prevent the tumor from spreading to other parts of your cat’s body (metastasise).

anatomy of cat's iris
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How Can You Care for a Cat With Iris Melanosis?

There are a few things that you can do for your cat if your vet suspects they are suffering from iris melanosis. Let’s take a look at what vets typically recommend.

Find an Eye Vet

The first step in caring for a cat with iris melanosis is to first visit a veterinarian who specializes in ophthalmology. This specialist can provide a thorough examination of your cat’s eyes and assess the extent of the pigmentation. They will establish a monitoring plan and may also recommend specific tests if necessary. It’s important to follow their recommendations closely to ensure that any changes will be detected and addressed as early as possible.

Monitoring

As mentioned earlier, another vital aspect of caring for a cat with iris melanosis is to monitor their eyes regularly. This means checking for changes in color or pigmentation, changes in the shape of the pupil or any redness or tearing.

Cats with iris melanoma are at higher risk of developing secondary glaucoma (increased pressure inside the eye) If you notice any changes, it’s important to contact your vet immediately. They may recommend additional tests or surgery.

A very useful and simple tool is to take pictures of your cat’s eyes regularly (as often as your ophthalmologist recommends or approximately once a month). That way, you can make sure you can detect any subtle changes and contact your vet as soon as you notice.

person taking picture of a cat
Image By: Beatriz Vera, Shutterstock

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What Are the Treatment Options for Cats With Iris Melanosis?

Iris melanosis is an irreversible benign change that does not require any treatment. However, if the cat develops an iris melanoma, the only treatment that is currently recommended is enucleation.

vet examining cat's eyes
Image Credit: Kachalkina Veronika, Shutterstock

Can Iris Melanosis Be Prevented?

Unfortunately, preventing iris melanosis in cats is currently impossible. However, you can make sure you monitor your cat’s eyes regularly and attend scheduled visits with your vet to have a full exam of your cat’s body including their eyes.

If your cat develops color changes in their iris, it is possible that your veterinary ophthalmologist recommends an iris biopsy to understand if melanoma has developed. After a biopsy, depending on the results, your vet may recommend to continue with close monitoring if melanoma has not developed, or early enucleation if it has.

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Conclusion

Iris melanosis is a benign condition that can cause flat, dark spots to develop on the iris of cats. While the condition is not harmful in itself, it can be the first stage of a malignant tumor called iris melanoma. It’s essential to seek specialist advice if you detect any changes to your cat’s eyes to identify the condition early on and have a monitoring or treatment plan in place


Featured Image Credit: Todorean-Gabriel, Shutterstock

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