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9 Best Cat Urine & Odor Removers (Enzyme Cleaners) – 2024 Reviews and Top Picks

Rachel Giordano

By Rachel Giordano

grey british shorthar cat pee urine carpet

Does your cat have a habit of peeing inside your home to mark its territory or show its displeasure?

Do they have a habit of peeing in the same spots over and over again? In this article, we have reviewed nine of the best enzymatic cat urine removers that can help rid your home of cat urine and its odor for good.

Keep reading our reviews to learn more about each of these products and determine which one is right for you.

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A Quick Comparison of Our Favorites (Updated 2024)

Rating Image Product Details
Best Overall
Winner
Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray
  • Bio-enzyme formula eliminates stains & odors entirely
  • Neutral scent with no chemical fragrance
  • Works on all surfaces
  • Budget Buy
    Second place
    Urine Gone Stain & Odor Eliminator Urine Gone Stain & Odor Eliminator
  • Easy to use
  • Non-toxic
  • Third place
    Rocco & Roxie Professional Strength Odor Eliminator Rocco & Roxie Professional Strength Odor Eliminator
  • Can be used on multiple surfaces
  • Color-safe
  • Pleasant smelling odor
  • Nature’s Miracle Stain & Odor Remover Nature’s Miracle Stain & Odor Remover
  • Organic ingredients
  • Can be used on multiple surfaces
  • Effective
  • ANGRY ORANGE Pet Odor Eliminator ANGRY ORANGE Pet Odor Eliminator
  • Non-toxic
  • Long-lasting
  • Works on many different surfaces
  • The 9 Best Cat Urine & Odor Removers

    1. Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray – Best Overall

    hepper enzyme cleaner spray

    Check Price on Hepper
    Scent Neutral
    Item weight 32 oz
    Intended surfaces Carpets, floors, fabrics, furniture, and more!
    Spray bottle Yes

    If you are looking for an enzymatic spray to eliminate cat urine stains, look no further than our very own Hepper Advanced Bio-Enzyme Pet Stain and Odor Eliminator Spray. This pre-mixed spray is safe to use on any surface, including carpet, hard floors, and furniture.

    It comes in a 32-ounce container and will last you a long time, even if your pet leaves behind a mess on the regular, as a little goes a long way. The unique formula, which contains live bio-enzymes, cuts straight to the core of the stain, eliminating them along with any odors. It will clean vomit, feces, drool, and urine with no problem, leaving behind only a neutral scent, so you know it is not masking the problem with fragrance. They’ll even refund your money if you are not 100% satisfied with it.

    For tougher, set-in stains, you may need to leave the solution in the area for a longer period of time for the spot to be removed entirely.

    This enzymatic cleaner will last and is efficient at lifting pet stains. With its neutral scent, strong enzymatic solution, and ease of use, we’re confident that this product is the overall best cat urine odor remover and enzymatic cleaner. Some users may like fragrances added, so we are looking into it, but don’t have any fragrance options at this time.

    Pros
    • Pre-mixed spray
    • Safe for carpet, hard floors, and furniture
    • Comes in a large, 32-ounce bottle
    • Fresh, neutral scent
    Cons
    • No fragrance varieties at the moment

    2. Urine Gone Stain & Odor Eliminator – Budget Buy

    Urine Gone, S Stain & Odor Eliminator

    Scent N/A
    Item weight 5 pounds
    Intended surfaces Wood, tile, carpet, litter boxes
    Spray bottle Yes

    At 24 ounces, the Urine Gone Stain and Odor Eliminator comes in a slightly smaller bottle than other products on this list but is a great alternative if you’re on a budget. It is available in two, three, or four packs via Amazon, making it easy to stock up for pet owners who find themselves cleaning up after their furry friends regularly.

    Though this product is less effective than the Hepper Enzyme Spray, it does the job, and users say it is very easy to use; all you have to do is spray the area, and no additional cleanup is required. As a bonus, the ingredients in this product are non-toxic, meaning it is safe to use around animals and children.

    Pros
    • Easy to use
    • Non-toxic
    Cons
    • Strong chemical odor
    • Requires more products to be effective

    3.  Rocco & Roxie Professional Strength Odor Eliminator

    Rocco & Roxie Professional Strength Stain & Odor Eliminator

    Scent N/A
    Item weight 2 pounds
    Intended surfaces 2 pounds
    Spray bottle Yes

    You can purchase either a 32-ounce or 1-gallon bottle of Rocco & Roxie Professional Strength Odor Eliminator. While this product is more expensive than other options on our list, it is an effective product that also happens to be color-safe. While some cleaning products have a very harsh chemical smell, the consensus on the Rocco & Roxie Professional Strength Odor Eliminator is that the odor is quite pleasant. In addition to stains caused by pet vomit or excrement, you can also use this product on other types of stains, such as wine.

    Overall, if you don’t mind spending a little bit more money on a product, the Rocco & Roxie Professional Strength Odor Eliminator is a quality product that can meet your diverse household stain needs.

    Pros
    • Can be used on multiple surfaces
    • Color-safe
    • Pleasant smelling odor
    Cons
    • More expensive than other options

    4. Nature’s Miracle Stain & Odor Remover

    Nature's Miracle Dog Stain and Odor Remover

    Scent Citrus
    Item weight 4 pounds
    Intended surfaces Carpets, hard floors, fabrics
    Spray bottle No

    Nature’s Miracle Stain & Odor Remover is a popular product made with all-natural, organic ingredients. As a result, it is safe to use in households with children or pets. It is an extremely versatile cleaner that is available in multiple sizes: 16 ounces, 32 punches, 64 ounces, or one gallon. While it can be used on a variety of different surfaces, you should be cautious about using Nature’s Miracle Stain & Odor Remover on delicate fabrics such as satin or silk.

    One negative to this product is that it is not particularly effective at preventing pets from marking your furniture and floors in the future. However, it is an overall solid product that is very effective at picking up stains.

    Pros
    • Organic ingredients
    • Can be used on multiple surfaces
    • Effective
    Cons
    • Not good for delicates
    • No spray nozzle
    • Strong scent

    5. ANGRY ORANGE Pet Odor Eliminator

    ANGRY ORANGE Pet Odor Eliminator

    Scent Orange
    Item weight 31 pounds
    Intended surfaces Multipurpose; works on wood, tile, grass, litter boxes, carpet, etc.
    Spray bottle Yes

    The Angry Orange Pet Odor Eliminator is another excellent choice for a cat urine and odor remover. You can purchase this product in a 32-ounce bottle that comes with a spray nozzle, which makes the application simple. You can use the Angry Orange Pet Odor Eliminator on any type of stain, from pet vomit to feces and urine.

    One of the biggest advantages of this product is how long-lasting its effects are; once you apply it, this product will keep foul odors at bay for up to 80 hours. It will also work on just about any surface you can think of, including carpet, your cat’s litter box, and even grass!

    Pros
    • Non-toxic
    • Long-lasting
    • Works on many different surfaces
    Cons
    • Spray bottle does not function well for all users

    6. Bubba’s Rowdy Friends Super Strength Commercial Enzyme Cleaner

    BUBBAS Super Strength Commercial Enzyme Cleaner

    Scent N/A
    Item weight 3 pounds
    Intended surfaces Wood, carpet, fabrics, litter boxes
    Spray bottle Yes

    Bubba’s Rowdy Friends Super Strength Commercial Enzyme Cleaner sure sounds like a product that can handle serious stains, and it is. In fact, it is one of the only products on our list of best enzymatic cat urine removers that is certified by the Carpet and Rug Institute. That means this product is highly effective at cleaning up stains and odors—especially those in your carpet. It works on other surfaces, too, including wood floors and even litter boxes.

    You can even use this product to spot-clean stains before you throw clothing in the washing machine. Something to keep in mind, however, is that if you use this product on light-colored fabrics, it may make stains worse.

    Pros
    • Carpet & Rug Institute certified
    • Works on multiple surfaces
    • Can spot-treat stains
    Cons
    • Strong scent

    7. Sunny & Honey Enzyme Pet Stain & Odor Miracle

    Pet Stain & Odor Miracle

    Scent Spring mint, light lavender, and fall spice
    Item weight 29 pounds
    Intended surfaces Rug, carpet, wood, laminate, concrete
    Spray bottle Yes

    The Pet Stain & Odor Miracle from Sunny & Honey provides lots of options for customers. Not only does this product come in two sizes—32 ounces and 1 gallon—but it is also available in three scents: spring mint, light lavender, and fall spice. This all-natural cleaner is great for organic messes such as pet urine, feces, and vomit. However, like Bubba’s Rowdy Friends Super Strength Cleaner, this cleaner can cause oil stains if you are not careful with your light-colored carpet and fabrics.

    One thing to note is that the smell of this product, however lovely it may seem, can be very strong. If you are sensitive to smells, you may want to consider an alternative option.

    Pros
    • Works on multiple surfaces
    • Cruelty-free
    • Scent options
    Cons
    • Very strong smelling

    8. Simple Solution Extreme Pet Stain and Odor Remover

    Simple Solution Extreme Pet Stain and Odor Remover

    Scent Spring breeze or unscented
    Item weight 2 pounds
    Intended surfaces Clothing, fabric, upholstery, bedding
    Spray bottle Yes

    You can purchase the Simple Solution Extreme Pet Stain and Odor Remover in either a 32-oz bottle with a nozzle or a one-gallon size refill. This product features a three-in-one nozzle that functions as a foam, spray, or mist. This Simple Solution product may be appropriate for older stains, but it is most helpful for fresh stains and odors in your home. While the three-in-one nozzle is an asset, note that the nozzle may not always function the way it is supposed to.

    You should also be aware that this particular formula can sometimes leave an oil stain, so it’s best to avoid using it on light-colored fabrics and carpets.

    Pros
    • Non-toxic
    • Effective
    Cons
    • Very strong smelling
    • Some customers had problems with the spray nozzle
    • Can sometimes stain clothing and other fabrics

    9. Lots of Lemon Pet Odor Eliminator

    Lots of Lemon Pet Odor Eliminator

    Scent Lemon
    Item weight 61 pounds
    Intended surfaces Hardwood floors, furniture, clothing, litter boxes
    Spray bottle Yes

    Last but not least, the Lots of Lemon Pet Odor Eliminator is an excellent product that combines essential oils and natural enzymes to beat odors and banish stains in your home. Because it is non-toxic, it is safe to use around children and pets; you can even use it in your cat’s litter box! The lemon scent is pleasant and much less overwhelming than many other chemical stain and odor removers on the market.

    One drawback of this product is that the lemon smell does last as long as stronger-smelling products on this list. If you are not completely satisfied with this product, the company will refund you, so trying this product is low-risk.

    Pros
    • Non-toxic
    • Money-back guarantee
    • Pleasant lemon smell
    Cons
    • Scent doesn’t last long

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    Buyer’s Guide – Choosing the Best Enzymatic Cat Urine Remover

    What Is An Enzymatic Cleaner?

    As you might expect, an enzymatic cleaner is a cleaner that contains enzymes, whose job it is to break down messes at a natural pH. They are very effective at breaking down stains and removing odors, unlike other products that tend to simply cover the odor.

    This is especially helpful when you have a pet that has gotten into the habit of using the bathroom in the same spot on your carpet—the familiar scent may encourage them to keep using the bathroom in that spot over and over again. If you can remove the odor altogether, you will also reduce the chances that the behavior will reoccur.

    What To Look for in an Enzymatic Cleaner

    Active Ingredients

    If you have young children, you will want to pay special attention to the ingredients list on any odor-removal product you purchase. Not all cleaning products are considered non-toxic, which means they may not be suitable to use around animals or children. If you want to eliminate marking behavior, check for ingredients that help get rid of ammonia smells, such as citrus scents.

    cleaning leather sofa_Lion Day, Shutterstock
    Image Credit: Lion Day, Shutterstock

    Intended Surfaces

    Many of the products on our list are intended for use on multiple different types of surfaces, but it is important to always double-check before you use a product on a stain. Some products are great at getting odors and stains off of hard surfaces, but they could be too harsh on delicate fabrics. If a product’s description doesn’t specifically state that it will work on a particular surface, you should probably look for a different product.

    Time Frame

    You won’t always notice stains or odors right away. When you find an old stain you want to remove, you want to make sure that the product you are using will work on tough, dried stains that have settled into your carpet. Make sure to read the product description and reviews to get a sense of whether or not a particular product is appropriate for old stains.

    hepper cat paw divider

    Final Thoughts

    We hope our reviews have helped you find a product that will work for you and your needs. The Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray is our pick for the best overall cat urine and odor remover because it not only works on many different types of surfaces, but it banishes odors completely.

    We thought the Urine Gone Stain & Odor Eliminator is a great alternative for those on a budget, though it has less staying power than the Hepper Bio-Enzyme Spray, it is just as effective at a lower price.

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    Featured Image Credit: Pixel-Shot, Shutterstock

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